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Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort
Osteoarthritis (OA) is a chronic degenerative joint disease, being the main cause of laboral inability. Decreased telomere size in peripheral blood leukocytes (PBL) has been correlated with age-related pathologies, like knee OA. In a dynamic approach, telomere-qPCR was performed to evaluate the rela...
Autores principales: | Guillén, Rebeca, Otero, Fátima, Mosquera, Alejandro, Vázquez-Mosquera, María, Rego-Pérez, Ignacio, Blanco, Francisco J., Fernández, José Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342605/ https://www.ncbi.nlm.nih.gov/pubmed/34354128 http://dx.doi.org/10.1038/s41598-021-95326-7 |
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