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In vivo imaging of mGlu5 receptor expression in humans with Fragile X Syndrome towards development of a potential biomarker

Fragile X Syndrome (FXS) is a neurodevelopmental disorder caused by silencing of the Fragile X Mental Retardation (FMR1) gene. The resulting loss of Fragile X Mental Retardation Protein (FMRP) leads to excessive glutamate signaling via metabotropic glutamate subtype 5 receptors (mGluR5) which has be...

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Detalles Bibliográficos
Autores principales:	Mody, Maria, Petibon, Yoann, Han, Paul, Kuruppu, Darshini, Ma, Chao, Yokell, Daniel, Neelamegam, Ramesh, Normandin, Marc D., Fakhri, Georges El, Brownell, Anna-Liisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342610/ https://www.ncbi.nlm.nih.gov/pubmed/34354107 http://dx.doi.org/10.1038/s41598-021-94967-y

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