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Male subfertility and oxidative stress
To date 15% of couples are suffering from infertility with 45–50% of males being responsible. With an increase in paternal age as well as various environmental and lifestyle factors worsening these figures are expected to increase. As the so-called free radical theory of infertility suggests, free r...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342954/ https://www.ncbi.nlm.nih.gov/pubmed/34340027 http://dx.doi.org/10.1016/j.redox.2021.102071 |
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author | Evans, Emily P.P. Scholten, Jorien T.M. Mzyk, Aldona Reyes-San-Martin, Claudia Llumbet, Arturo E. Hamoh, Thamir Arts, Eus G.J.M. Schirhagl, Romana Cantineau, Astrid E.P. |
author_facet | Evans, Emily P.P. Scholten, Jorien T.M. Mzyk, Aldona Reyes-San-Martin, Claudia Llumbet, Arturo E. Hamoh, Thamir Arts, Eus G.J.M. Schirhagl, Romana Cantineau, Astrid E.P. |
author_sort | Evans, Emily P.P. |
collection | PubMed |
description | To date 15% of couples are suffering from infertility with 45–50% of males being responsible. With an increase in paternal age as well as various environmental and lifestyle factors worsening these figures are expected to increase. As the so-called free radical theory of infertility suggests, free radicals or reactive oxygen species (ROS) play an essential role in this process. However, ROS also fulfill important functions for instance in sperm maturation. The aim of this review article is to discuss the role reactive oxygen species play in male fertility and how these are influenced by lifestyle, age or disease. We will further discuss how these ROS are measured and how they can be avoided during in-vitro fertilization. |
format | Online Article Text |
id | pubmed-8342954 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-83429542021-08-11 Male subfertility and oxidative stress Evans, Emily P.P. Scholten, Jorien T.M. Mzyk, Aldona Reyes-San-Martin, Claudia Llumbet, Arturo E. Hamoh, Thamir Arts, Eus G.J.M. Schirhagl, Romana Cantineau, Astrid E.P. Redox Biol Review Article To date 15% of couples are suffering from infertility with 45–50% of males being responsible. With an increase in paternal age as well as various environmental and lifestyle factors worsening these figures are expected to increase. As the so-called free radical theory of infertility suggests, free radicals or reactive oxygen species (ROS) play an essential role in this process. However, ROS also fulfill important functions for instance in sperm maturation. The aim of this review article is to discuss the role reactive oxygen species play in male fertility and how these are influenced by lifestyle, age or disease. We will further discuss how these ROS are measured and how they can be avoided during in-vitro fertilization. Elsevier 2021-07-18 /pmc/articles/PMC8342954/ /pubmed/34340027 http://dx.doi.org/10.1016/j.redox.2021.102071 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Article Evans, Emily P.P. Scholten, Jorien T.M. Mzyk, Aldona Reyes-San-Martin, Claudia Llumbet, Arturo E. Hamoh, Thamir Arts, Eus G.J.M. Schirhagl, Romana Cantineau, Astrid E.P. Male subfertility and oxidative stress |
title | Male subfertility and oxidative stress |
title_full | Male subfertility and oxidative stress |
title_fullStr | Male subfertility and oxidative stress |
title_full_unstemmed | Male subfertility and oxidative stress |
title_short | Male subfertility and oxidative stress |
title_sort | male subfertility and oxidative stress |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342954/ https://www.ncbi.nlm.nih.gov/pubmed/34340027 http://dx.doi.org/10.1016/j.redox.2021.102071 |
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