Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterized by excessive deposition of extracellular matrix in the lung with fibroblast-to-myofibroblast transition, leading to chronically compromising lung function and death. However, very little is known about the metabolic alterations of fibroblasts in I...

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Detalles Bibliográficos
Autores principales: Wang, Ziwen, Chen, Long, Huang, Yu, Luo, Min, Wang, Huilan, Jiang, Zhongyong, Zheng, Jiancheng, Yang, Zeyu, Chen, Zelin, Zhang, Chi, Long, Lei, Wang, Yawei, Li, Xueru, Liao, Fengying, Gan, Yibo, Luo, Peng, Liu, Yunsheng, Wang, Yu, XuTan, Zhou, Ziyuan, Zhang, Aihua, Shi, Chunmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342973/
https://www.ncbi.nlm.nih.gov/pubmed/34343908
http://dx.doi.org/10.1016/j.redox.2021.102082

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