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Cytokine Release Syndrome Is an Independent Risk Factor Associated With Platelet Transfusion Refractoriness After CAR-T Therapy for Relapsed/Refractory Acute Lymphoblastic Leukemia

Background: Chimeric antigen receptor T cell (CAR-T) therapy is successful in improving treatment outcomes for relapsed/refractory acute lymphoblastic leukemia (R/R ALL). However, toxicities associated with CAR-T therapy are being increasingly identified. Pancytopenia is one of the most common compl...

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Detalles Bibliográficos
Autores principales: Liu, Yadan, Liang, Bin, Liu, Yan, Wei, Guoqing, Wu, Wenjun, Yang, Luxin, Yang, Li, Huang, He, Xie, Jue, Hu, Yongxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343018/
https://www.ncbi.nlm.nih.gov/pubmed/34366854
http://dx.doi.org/10.3389/fphar.2021.702152