Malignant Hyperthermia Syndrome: A Clinical Case Report

Malignant hyperthermia is a pharmacogenetic disorder. It manifests as a hypercatabolic skeletal muscle syndrome linked to inhaled volatile anesthetics or depolarizing muscle relaxants. Its clinical signs and symptoms are tachycardia, hyperthermia, hypercapnia, acidosis, muscle rigidity, rhabdomyolys...

Descripción completa

Detalles Bibliográficos
Autores principales: Acosta, Isabel Sánchez-Molina, de Cos, Guillermo Velasco, Fernández, Matilde Toval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343040/
https://www.ncbi.nlm.nih.gov/pubmed/34421497
_version_ 1783734194309955584
author Acosta, Isabel Sánchez-Molina
de Cos, Guillermo Velasco
Fernández, Matilde Toval
author_facet Acosta, Isabel Sánchez-Molina
de Cos, Guillermo Velasco
Fernández, Matilde Toval
author_sort Acosta, Isabel Sánchez-Molina
collection PubMed
description Malignant hyperthermia is a pharmacogenetic disorder. It manifests as a hypercatabolic skeletal muscle syndrome linked to inhaled volatile anesthetics or depolarizing muscle relaxants. Its clinical signs and symptoms are tachycardia, hyperthermia, hypercapnia, acidosis, muscle rigidity, rhabdomyolysis, hyperkalemia, arrhythmia and renal failure. Mortality without specific treatment is 80% and decreases to 5% with the use of dantrolene sodium. This article presents the case of a 39-year-old patient admitted to the Intensive Care Unit for malignant hyperthermia after surgery for septoplasty plus turbinoplasty.
format Online
Article
Text
id pubmed-8343040
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Communications and Publications Division (CPD) of the IFCC
record_format MEDLINE/PubMed
spelling pubmed-83430402021-08-20 Malignant Hyperthermia Syndrome: A Clinical Case Report Acosta, Isabel Sánchez-Molina de Cos, Guillermo Velasco Fernández, Matilde Toval EJIFCC Case Report Malignant hyperthermia is a pharmacogenetic disorder. It manifests as a hypercatabolic skeletal muscle syndrome linked to inhaled volatile anesthetics or depolarizing muscle relaxants. Its clinical signs and symptoms are tachycardia, hyperthermia, hypercapnia, acidosis, muscle rigidity, rhabdomyolysis, hyperkalemia, arrhythmia and renal failure. Mortality without specific treatment is 80% and decreases to 5% with the use of dantrolene sodium. This article presents the case of a 39-year-old patient admitted to the Intensive Care Unit for malignant hyperthermia after surgery for septoplasty plus turbinoplasty. The Communications and Publications Division (CPD) of the IFCC 2021-06-29 /pmc/articles/PMC8343040/ /pubmed/34421497 Text en Copyright © 2021 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This is a Platinum Open Access Journal distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Acosta, Isabel Sánchez-Molina
de Cos, Guillermo Velasco
Fernández, Matilde Toval
Malignant Hyperthermia Syndrome: A Clinical Case Report
title Malignant Hyperthermia Syndrome: A Clinical Case Report
title_full Malignant Hyperthermia Syndrome: A Clinical Case Report
title_fullStr Malignant Hyperthermia Syndrome: A Clinical Case Report
title_full_unstemmed Malignant Hyperthermia Syndrome: A Clinical Case Report
title_short Malignant Hyperthermia Syndrome: A Clinical Case Report
title_sort malignant hyperthermia syndrome: a clinical case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343040/
https://www.ncbi.nlm.nih.gov/pubmed/34421497
work_keys_str_mv AT acostaisabelsanchezmolina malignanthyperthermiasyndromeaclinicalcasereport
AT decosguillermovelasco malignanthyperthermiasyndromeaclinicalcasereport
AT fernandezmatildetoval malignanthyperthermiasyndromeaclinicalcasereport

Ejemplares similares