Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1

Immune checkpoint inhibitors such as anti-PD-1 have revolutionized the field of oncology over the past decade. Nevertheless, the majority of patients do not benefit from them. Virotherapy is a flexible tool that can be used to stimulate and/or recruit different immune populations. T-cell enabling vi...

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Detalles Bibliográficos
Autores principales: Cervera-Carrascon, Victor, Quixabeira, Dafne C. A., Santos, Joao M., Havunen, Riikka, Milenova, Ioanna, Verhoeff, Jan, Heiniö, Camilla, Zafar, Sadia, Garcia-Vallejo, Juan J., van Beusechem, Victor W., de Gruijl, Tanja D., Kalervo, Aino, Sorsa, Suvi, Kanerva, Anna, Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343222/
https://www.ncbi.nlm.nih.gov/pubmed/34367166
http://dx.doi.org/10.3389/fimmu.2021.706517

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