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Acute effects of dapagliflozin on renal oxygenation and perfusion in type 1 diabetes with albuminuria: A randomised, double-blind, placebo-controlled crossover trial

BACKGROUND: Inhibitors of the sodium-glucose cotransporter 2 (SGLT2) slow the progression of diabetic kidney disease, possibly by reducing the proximal tubule transport workload with subsequent improvement of renal oxygenation. We aimed to test this hypothesis in individuals with type 1 diabetes and...

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Detalles Bibliográficos
Autores principales: Laursen, Jens Christian, Søndergaard-Heinrich, Niels, de Melo, Joana Mendes Lopes, Haddock, Bryan, Rasmussen, Ida Kirstine Bull, Safavimanesh, Farzaneh, Hansen, Christian Stevns, Størling, Joachim, Larsson, Henrik Bo Wiberg, Groop, Per-Henrik, Frimodt-Møller, Marie, Andersen, Ulrik Bjørn, Rossing, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343250/
https://www.ncbi.nlm.nih.gov/pubmed/34386735
http://dx.doi.org/10.1016/j.eclinm.2021.100895