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Acute effects of dapagliflozin on renal oxygenation and perfusion in type 1 diabetes with albuminuria: A randomised, double-blind, placebo-controlled crossover trial
BACKGROUND: Inhibitors of the sodium-glucose cotransporter 2 (SGLT2) slow the progression of diabetic kidney disease, possibly by reducing the proximal tubule transport workload with subsequent improvement of renal oxygenation. We aimed to test this hypothesis in individuals with type 1 diabetes and...
Autores principales: | Laursen, Jens Christian, Søndergaard-Heinrich, Niels, de Melo, Joana Mendes Lopes, Haddock, Bryan, Rasmussen, Ida Kirstine Bull, Safavimanesh, Farzaneh, Hansen, Christian Stevns, Størling, Joachim, Larsson, Henrik Bo Wiberg, Groop, Per-Henrik, Frimodt-Møller, Marie, Andersen, Ulrik Bjørn, Rossing, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343250/ https://www.ncbi.nlm.nih.gov/pubmed/34386735 http://dx.doi.org/10.1016/j.eclinm.2021.100895 |
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