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Occurrence of High Microsatellite-Instability/Mismatch Repair Deficiency in Nearly 2,000 Human Adenocarcinomas of the Gastrointestinal Tract, Pancreas, and Bile Ducts: A Study From a Large German Comprehensive Cancer Center

INTRODUCTION: Knowledge of the high microsatellite-instability (MSI-H)/mismatch repair deficiency (MMRd) status is of increasing interest for personalized neoadjuvant or adjuvant therapy planning. Only a few studies are available on MSI-H distribution in the Northern European Caucasian patient popul...

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Detalles Bibliográficos
Autores principales: Quaas, Alexander, Rehkaemper, Jan, Rueschoff, Josef, Pamuk, Aylin, Zander, Thomas, Hillmer, Axel, Siemanowski, Janna, Wittig, Jana, Buettner, Reinhard, Plum, Patrick, Popp, Felix, Gebauer, Florian, Bruns, Christiane Josephine, Loeser, Heike, Alakus, Hakan, Schoemig-Markiefka, Birgid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343401/
https://www.ncbi.nlm.nih.gov/pubmed/34367937
http://dx.doi.org/10.3389/fonc.2021.569475