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Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report
BACKGROUND: Coronary embolism is an important non-atherosclerotic cause of acute myocardial infarction (AMI) that requires an individualized diagnostic and therapeutic approach. Although certain angiographic criteria exist that render an embolic origin likely, uncertainty remains. Optical coherence...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343470/ https://www.ncbi.nlm.nih.gov/pubmed/34377894 http://dx.doi.org/10.1093/ehjcr/ytab115 |
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author | Kavaliauskaite, Raminta Otsuka, Tatsuhiko Ueki, Yasushi Räber, Lorenz |
author_facet | Kavaliauskaite, Raminta Otsuka, Tatsuhiko Ueki, Yasushi Räber, Lorenz |
author_sort | Kavaliauskaite, Raminta |
collection | PubMed |
description | BACKGROUND: Coronary embolism is an important non-atherosclerotic cause of acute myocardial infarction (AMI) that requires an individualized diagnostic and therapeutic approach. Although certain angiographic criteria exist that render an embolic origin likely, uncertainty remains. Optical coherence tomography (OCT) is a high-resolution intracoronary imaging technology that enables visualization of thrombus and the underlying coronary vessel wall, which may be helpful to distinguish between an atherosclerotic and non-atherosclerotic origin of AMI. CASE SUMMARY : A 50-year-old male was admitted with ongoing chest pain. Eleven years ago, he underwent implantation of a mechanical aortic valve prosthesis due to degenerated bicuspid valve with normal coronaries on preoperative angiography. The electrocardiogram showed anterior ST-segment elevation. Emergent angiography revealed total occlusion of the proximal left anterior descending artery (LAD). Thrombus was aspirated along with administration of intravenous glycoprotein IIbIIIa inhibitor. Except the apical part of the LAD showing distal embolization, coronary flow was completely re-established with no evidence of significant atherosclerosis. Stents were not implanted on the basis of the OCT finding, which demonstrated at the site of occlusion a normal vessel wall without atherosclerosis that could explain an erosion or plaque rupture event. Transoesophageal echocardiography confirmed a floating structure in the left ventricular outflow tract, suggesting that an embolus originating from the prosthetic aortic valve obstructed the LAD. The international normalized ratio 2 days prior to presentation measured 1.9. DISCUSSION : This case illustrates the utility of OCT to rule out the atherosclerotic aetiology of myocardial infarction and to avoid unnecessary stenting. |
format | Online Article Text |
id | pubmed-8343470 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-83434702021-08-09 Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report Kavaliauskaite, Raminta Otsuka, Tatsuhiko Ueki, Yasushi Räber, Lorenz Eur Heart J Case Rep Case Report BACKGROUND: Coronary embolism is an important non-atherosclerotic cause of acute myocardial infarction (AMI) that requires an individualized diagnostic and therapeutic approach. Although certain angiographic criteria exist that render an embolic origin likely, uncertainty remains. Optical coherence tomography (OCT) is a high-resolution intracoronary imaging technology that enables visualization of thrombus and the underlying coronary vessel wall, which may be helpful to distinguish between an atherosclerotic and non-atherosclerotic origin of AMI. CASE SUMMARY : A 50-year-old male was admitted with ongoing chest pain. Eleven years ago, he underwent implantation of a mechanical aortic valve prosthesis due to degenerated bicuspid valve with normal coronaries on preoperative angiography. The electrocardiogram showed anterior ST-segment elevation. Emergent angiography revealed total occlusion of the proximal left anterior descending artery (LAD). Thrombus was aspirated along with administration of intravenous glycoprotein IIbIIIa inhibitor. Except the apical part of the LAD showing distal embolization, coronary flow was completely re-established with no evidence of significant atherosclerosis. Stents were not implanted on the basis of the OCT finding, which demonstrated at the site of occlusion a normal vessel wall without atherosclerosis that could explain an erosion or plaque rupture event. Transoesophageal echocardiography confirmed a floating structure in the left ventricular outflow tract, suggesting that an embolus originating from the prosthetic aortic valve obstructed the LAD. The international normalized ratio 2 days prior to presentation measured 1.9. DISCUSSION : This case illustrates the utility of OCT to rule out the atherosclerotic aetiology of myocardial infarction and to avoid unnecessary stenting. Oxford University Press 2021-07-30 /pmc/articles/PMC8343470/ /pubmed/34377894 http://dx.doi.org/10.1093/ehjcr/ytab115 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Kavaliauskaite, Raminta Otsuka, Tatsuhiko Ueki, Yasushi Räber, Lorenz Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
title | Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
title_full | Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
title_fullStr | Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
title_full_unstemmed | Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
title_short | Coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
title_sort | coronary embolism due to possible thrombosis of prosthetic aortic valve - the role of optical coherence tomography: case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343470/ https://www.ncbi.nlm.nih.gov/pubmed/34377894 http://dx.doi.org/10.1093/ehjcr/ytab115 |
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