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Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021

Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from F...

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Autores principales: de Gier, Brechje, Andeweg, Stijn, Joosten, Rosa, ter Schegget, Ronald, Smorenburg, Naomi, van de Kassteele, Jan, Hahné, Susan JM, van den Hof, Susan, de Melker, Hester E, Knol, Mirjam J, Hofhuis, Agnetha, Teirlinck, Anne, van Lier, Alies, Boudewijns, Bronke, Verstraten, Carolien, Willekens, Guido, Veldhuijzen, Irene, Polman, Jan, Alblas, Jeroen, van Heereveld, Janneke, Heijne, Janneke, Bulsink, Kirsten, Wielders, Lieke, van Asten, Liselotte, Jenniskens, Liz, Soetens, Loes, Mulder, Maarten, Schipper, Maarten, de Lange, Marit, Neppelenbroek, Nienke, van den Berg, Patrick, de Oliveira Bressane Lima, Priscila, van Gaalen, Rolina, Wijburg, Sara, van Iersel, Senna, de Bruijn, Siméon, Wierenga, Sjoerd, Lanooij, Susan, Keijser, Sylvia, Smit, Tara, Klinkenberg, Don, Backer, Jantien, de Boer, Pieter, McDonald, Scott, Maxwell, Amber, Niessen, Annabel, Berry, Danytza, van Wees, Daphne, van Meijeren, Dimphey, Vos, Eric R.A., Dijkstra, Frederika, Kemmeren, Jeanet, Ainslie, Kylie, Middeldorp, Marit, Kooijman, Marjolein, Knol, Mirjam, Zadeh, Shahabeh Abbas, Faber, Timor, van Hoek, Albert Jan, Geubbels, Eveline, de Melker, Hester, Wallinga, Jacco, van Gageldonk-Lafeber, Rianne, Hahne, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343550/
https://www.ncbi.nlm.nih.gov/pubmed/34355689
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.31.2100640
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author de Gier, Brechje
Andeweg, Stijn
Joosten, Rosa
ter Schegget, Ronald
Smorenburg, Naomi
van de Kassteele, Jan
Hahné, Susan JM
van den Hof, Susan
de Melker, Hester E
Knol, Mirjam J
Hofhuis, Agnetha
Teirlinck, Anne
van Lier, Alies
Boudewijns, Bronke
Verstraten, Carolien
Willekens, Guido
Veldhuijzen, Irene
Polman, Jan
van de Kassteele, Jan
Alblas, Jeroen
van Heereveld, Janneke
Heijne, Janneke
Bulsink, Kirsten
Wielders, Lieke
van Asten, Liselotte
Jenniskens, Liz
Soetens, Loes
Mulder, Maarten
Schipper, Maarten
de Lange, Marit
Smorenburg, Naomi
Neppelenbroek, Nienke
van den Berg, Patrick
de Oliveira Bressane Lima, Priscila
van Gaalen, Rolina
Wijburg, Sara
van Iersel, Senna
de Bruijn, Siméon
Andeweg, Stijn
Wierenga, Sjoerd
Lanooij, Susan
Keijser, Sylvia
Smit, Tara
Klinkenberg, Don
Backer, Jantien
de Boer, Pieter
McDonald, Scott
Maxwell, Amber
Niessen, Annabel
de Gier, Brechje
Berry, Danytza
van Wees, Daphne
van Meijeren, Dimphey
Vos, Eric R.A.
Dijkstra, Frederika
Kemmeren, Jeanet
Ainslie, Kylie
Middeldorp, Marit
Kooijman, Marjolein
Knol, Mirjam
Zadeh, Shahabeh Abbas
Faber, Timor
van Hoek, Albert Jan
Geubbels, Eveline
de Melker, Hester
Wallinga, Jacco
van Gageldonk-Lafeber, Rianne
Hahne, Susan
van den Hof, Susan
author_facet de Gier, Brechje
Andeweg, Stijn
Joosten, Rosa
ter Schegget, Ronald
Smorenburg, Naomi
van de Kassteele, Jan
Hahné, Susan JM
van den Hof, Susan
de Melker, Hester E
Knol, Mirjam J
Hofhuis, Agnetha
Teirlinck, Anne
van Lier, Alies
Boudewijns, Bronke
Verstraten, Carolien
Willekens, Guido
Veldhuijzen, Irene
Polman, Jan
van de Kassteele, Jan
Alblas, Jeroen
van Heereveld, Janneke
Heijne, Janneke
Bulsink, Kirsten
Wielders, Lieke
van Asten, Liselotte
Jenniskens, Liz
Soetens, Loes
Mulder, Maarten
Schipper, Maarten
de Lange, Marit
Smorenburg, Naomi
Neppelenbroek, Nienke
van den Berg, Patrick
de Oliveira Bressane Lima, Priscila
van Gaalen, Rolina
Wijburg, Sara
van Iersel, Senna
de Bruijn, Siméon
Andeweg, Stijn
Wierenga, Sjoerd
Lanooij, Susan
Keijser, Sylvia
Smit, Tara
Klinkenberg, Don
Backer, Jantien
de Boer, Pieter
McDonald, Scott
Maxwell, Amber
Niessen, Annabel
de Gier, Brechje
Berry, Danytza
van Wees, Daphne
van Meijeren, Dimphey
Vos, Eric R.A.
Dijkstra, Frederika
Kemmeren, Jeanet
Ainslie, Kylie
Middeldorp, Marit
Kooijman, Marjolein
Knol, Mirjam
Zadeh, Shahabeh Abbas
Faber, Timor
van Hoek, Albert Jan
Geubbels, Eveline
de Melker, Hester
Wallinga, Jacco
van Gageldonk-Lafeber, Rianne
Hahne, Susan
van den Hof, Susan
author_sort de Gier, Brechje
collection PubMed
description Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63–77).
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spelling pubmed-83435502021-08-20 Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021 de Gier, Brechje Andeweg, Stijn Joosten, Rosa ter Schegget, Ronald Smorenburg, Naomi van de Kassteele, Jan Hahné, Susan JM van den Hof, Susan de Melker, Hester E Knol, Mirjam J Hofhuis, Agnetha Teirlinck, Anne van Lier, Alies Boudewijns, Bronke Verstraten, Carolien Willekens, Guido Veldhuijzen, Irene Polman, Jan van de Kassteele, Jan Alblas, Jeroen van Heereveld, Janneke Heijne, Janneke Bulsink, Kirsten Wielders, Lieke van Asten, Liselotte Jenniskens, Liz Soetens, Loes Mulder, Maarten Schipper, Maarten de Lange, Marit Smorenburg, Naomi Neppelenbroek, Nienke van den Berg, Patrick de Oliveira Bressane Lima, Priscila van Gaalen, Rolina Wijburg, Sara van Iersel, Senna de Bruijn, Siméon Andeweg, Stijn Wierenga, Sjoerd Lanooij, Susan Keijser, Sylvia Smit, Tara Klinkenberg, Don Backer, Jantien de Boer, Pieter McDonald, Scott Maxwell, Amber Niessen, Annabel de Gier, Brechje Berry, Danytza van Wees, Daphne van Meijeren, Dimphey Vos, Eric R.A. Dijkstra, Frederika Kemmeren, Jeanet Ainslie, Kylie Middeldorp, Marit Kooijman, Marjolein Knol, Mirjam Zadeh, Shahabeh Abbas Faber, Timor van Hoek, Albert Jan Geubbels, Eveline de Melker, Hester Wallinga, Jacco van Gageldonk-Lafeber, Rianne Hahne, Susan van den Hof, Susan Euro Surveill Rapid Communication Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63–77). European Centre for Disease Prevention and Control (ECDC) 2021-08-05 /pmc/articles/PMC8343550/ /pubmed/34355689 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.31.2100640 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
de Gier, Brechje
Andeweg, Stijn
Joosten, Rosa
ter Schegget, Ronald
Smorenburg, Naomi
van de Kassteele, Jan
Hahné, Susan JM
van den Hof, Susan
de Melker, Hester E
Knol, Mirjam J
Hofhuis, Agnetha
Teirlinck, Anne
van Lier, Alies
Boudewijns, Bronke
Verstraten, Carolien
Willekens, Guido
Veldhuijzen, Irene
Polman, Jan
van de Kassteele, Jan
Alblas, Jeroen
van Heereveld, Janneke
Heijne, Janneke
Bulsink, Kirsten
Wielders, Lieke
van Asten, Liselotte
Jenniskens, Liz
Soetens, Loes
Mulder, Maarten
Schipper, Maarten
de Lange, Marit
Smorenburg, Naomi
Neppelenbroek, Nienke
van den Berg, Patrick
de Oliveira Bressane Lima, Priscila
van Gaalen, Rolina
Wijburg, Sara
van Iersel, Senna
de Bruijn, Siméon
Andeweg, Stijn
Wierenga, Sjoerd
Lanooij, Susan
Keijser, Sylvia
Smit, Tara
Klinkenberg, Don
Backer, Jantien
de Boer, Pieter
McDonald, Scott
Maxwell, Amber
Niessen, Annabel
de Gier, Brechje
Berry, Danytza
van Wees, Daphne
van Meijeren, Dimphey
Vos, Eric R.A.
Dijkstra, Frederika
Kemmeren, Jeanet
Ainslie, Kylie
Middeldorp, Marit
Kooijman, Marjolein
Knol, Mirjam
Zadeh, Shahabeh Abbas
Faber, Timor
van Hoek, Albert Jan
Geubbels, Eveline
de Melker, Hester
Wallinga, Jacco
van Gageldonk-Lafeber, Rianne
Hahne, Susan
van den Hof, Susan
Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
title Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
title_full Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
title_fullStr Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
title_full_unstemmed Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
title_short Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021
title_sort vaccine effectiveness against sars-cov-2 transmission and infections among household and other close contacts of confirmed cases, the netherlands, february to may 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343550/
https://www.ncbi.nlm.nih.gov/pubmed/34355689
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.31.2100640
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