Cargando…

Kir4.1 may represent a novel therapeutic target for diabetic retinopathy (Review)

As the major cause of irreversible loss of vision in adults, diabetic retinopathy (DR) is one of the most serious complications of diabetes. The imbalance of the retinal microenvironment and destruction of the blood-retinal barrier have a significant role in the progression of DR. Inward rectifying...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiaoyu, Lv, Jiajun, Li, Jiazhi, Ren, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343704/ https://www.ncbi.nlm.nih.gov/pubmed/34373707 http://dx.doi.org/10.3892/etm.2021.10453

Ejemplares similares

KIR3DL2 may represent a novel therapeutic target in aggressive systemic peripheral T-cell lymphoma
por: Decroos, Amandine, et al.
Publicado: (2023)

Astrocytic Kir4.1 potassium channels as a novel therapeutic target for epilepsy and mood disorders
por: Ohno, Yukihiro
Publicado: (2018)

Thioredoxin-interacting protein in diabetic retinal neurodegeneration: A novel potential therapeutic target for diabetic retinopathy
por: Liu, Chengzhi, et al.
Publicado: (2022)

Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes
por: Alex, Alpha, et al.
Publicado: (2020)

KIR4.1 Antibodies as Biomarkers in Multiple Sclerosis
por: Wunsch, Marie, et al.
Publicado: (2014)

Autoantibodies to Potassium Channel KIR4.1 in Multiple Sclerosis
por: Schneider, Raphael
Publicado: (2013)

EAST/SeSAME Syndrome and Beyond: The Spectrum of Kir4.1- and Kir5.1-Associated Channelopathies
por: Lo, Jacky, et al.
Publicado: (2022)

Diabetic Retinopathy and Inflammation: Novel Therapeutic Targets
por: Rangasamy, Sampathkumar, et al.
Publicado: (2012)

Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis
por: Shang, Lijun, et al.
Publicado: (2009)

Expression of Kir4.1 and Kir5.1 inwardly rectifying potassium channels in oligodendrocytes, the myelinating cells of the CNS
por: Brasko, C., et al.
Publicado: (2016)

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity
por: Schirmer, Lucas, et al.
Publicado: (2018)

Lack of KIR4.1 autoantibodies in Japanese patients with MS and NMO
por: Higuchi, Osamu, et al.
Publicado: (2016)

Anti-Kir4.1 Antibodies in Multiple Sclerosis: Specificity and Pathogenicity
por: Imamura, Michie, et al.
Publicado: (2020)

Kir4.1 Dysfunction in the Pathophysiology of Depression: A Systematic Review
por: Della Vecchia, Stefania, et al.
Publicado: (2021)

Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure
por: Du, Mengmeng, et al.
Publicado: (2018)

Kir4.1 is coexpressed with stemness markers in activated astrocytes in the injured brain and a Kir4.1 inhibitor BaCl(2) negatively regulates neurosphere formation in culture
por: Kwon, Jae-Kyung, et al.
Publicado: (2021)

Biophysical and Molecular Mechanisms Underlying the Modulation of Heteromeric Kir4.1–Kir5.1 Channels by Co(2) and Ph
por: Yang, Zhenjiang, et al.
Publicado: (2000)

Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels
por: Shang, Lijun, et al.
Publicado: (2007)

Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter
por: Zhang, Dan-Dan, et al.
Publicado: (2023)

Inwardly Rectifying Potassium Channel Kir4.1 as a Novel Modulator of BDNF Expression in Astrocytes
por: Ohno, Yukihiro, et al.
Publicado: (2018)

The Neuroglial Potassium Cycle during Neurotransmission: Role of Kir4.1 Channels
por: Sibille, Jérémie, et al.
Publicado: (2015)

MeCP2 Deficiency Leads to Loss of Glial Kir4.1
por: Kahanovitch, Uri, et al.
Publicado: (2018)

Role of Astrocytic Inwardly Rectifying Potassium (Kir) 4.1 Channels in Epileptogenesis
por: Kinboshi, Masato, et al.
Publicado: (2020)

Inwardly rectifying potassium channels (Kir) in central nervous system glia: a special role for Kir4.1 in glial functions
por: Butt, Arthur M, et al.
Publicado: (2006)

Deeper and Deeper on the Role of BK and Kir4.1 Channels in Glioblastoma Invasiveness: A Novel Summative Mechanism?
por: Brandalise, Federico, et al.
Publicado: (2020)

KIR4.1: K(+) Channel Illusion or Reality in the Autoimmune Pathogenesis of Multiple Sclerosis
por: Gu, Chen
Publicado: (2016)

Antiepileptic Drugs Elevate Astrocytic Kir4.1 Expression in the Rat Limbic Region
por: Mukai, Takahiro, et al.
Publicado: (2018)

Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases
por: Ohno, Yukihiro, et al.
Publicado: (2021)

Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice
por: Méndez-González, Miguel P., et al.
Publicado: (2020)

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
por: Kelley, Kevin W., et al.
Publicado: (2018)

Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke
por: Hong, Xiaoqi, et al.
Publicado: (2022)

Kir4.1/Kir5.1 channels possess strong intrinsic inward rectification determined by a voltage-dependent K(+)-flux gating mechanism
por: Marmolejo-Murillo, Leticia G., et al.
Publicado: (2021)

ROCK as a Therapeutic Target of Diabetic Retinopathy
por: Arita, Ryoichi, et al.
Publicado: (2010)

Neuroprotection as a Therapeutic Target for Diabetic Retinopathy
por: Hernández, Cristina, et al.
Publicado: (2016)

Molecular Mechanisms of Diabetic Retinopathy, General Preventive Strategies, and Novel Therapeutic Targets
por: Safi, Sher Zaman, et al.
Publicado: (2014)

Oestrogen Receptor Isoforms May Represent a Therapeutic Target in Oesophageal Adenocarcinoma
por: Due, Steven L., et al.
Publicado: (2022)

The effect of high-dietary K(+) (HK) on Kir4.1/Kir5.1 and ROMK in the distal convoluted tubule (DCT) is not affected by gender and Cl(−) content of the diet
por: Meng, Xin-Xin, et al.
Publicado: (2022)

Proteomics identifies new potential therapeutic targets of diabetic retinopathy
por: Zhou, Huanran, et al.
Publicado: (2022)

Differential expression of Kir4.1 and aquaporin 4 in the retina from endotoxin-induced uveitis rat
por: Liu, Xiao-Qiang, et al.
Publicado: (2007)

Spatial and temporal dissociation of AQP4 and Kir4.1 expression during induction of refractive errors
por: Goodyear, Melinda J., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_rshcp5bs0oes0c3rjqjn2a5tn9