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A high CD8 to FOXP3 ratio in the tumor stroma and expression of PTEN in tumor cells are associated with improved survival in non-metastatic triple-negative breast carcinoma
BACKGROUND: Triple-negative mammary carcinoma (TNBC) is an aggressive breast cancer subtype associated with dismal prognosis. The interaction between the immune system and the cancer cells plays a crucial role in tumor development and progression. However, it is still unclear how each diverse cell o...
Autores principales: | Tavares, Monique C., Sampaio, Cristina D., Lima, Geraldine E., Andrade, Victor P., Gonçalves, Daniel G., Macedo, Mariana P., Cordeiro de Lima, Vladmir C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343973/ https://www.ncbi.nlm.nih.gov/pubmed/34362334 http://dx.doi.org/10.1186/s12885-021-08636-4 |
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