Cargando…

Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy

Background: Efficient and specific induction of cell death in liver cancer is urgently needed. In this study, we aimed to design an exosome-based platform to deliver ferroptosis inducer (Erastin, Er) and photosensitizer (Rose Bengal, RB) into tumor tissues with high specificity. Methods: Exosome don...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Jianbing, Wan, Zhuo, Wang, Cong, Lu, Fan, Wei, Mengying, Wang, Desheng, Hao, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344009/ https://www.ncbi.nlm.nih.gov/pubmed/34373736 http://dx.doi.org/10.7150/thno.59121

Ejemplares similares

ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy
por: Wan, Zhuo, et al.
Publicado: (2022)

Ternary cocktail nanoparticles for sequential chemo-photodynamic therapy
por: Fan, Li, et al.
Publicado: (2017)

Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy
por: Zhan, Qi, et al.
Publicado: (2020)

Self-assembly of nanomicelles with rationally designed multifunctional building blocks for synergistic chemo-photodynamic therapy
por: Gong, Guidong, et al.
Publicado: (2022)

Amphiphilic block polymer-based self-assembly of high payload nanoparticles for efficient combinatorial chemo-photodynamic therapy
por: Ma, Qisan, et al.
Publicado: (2020)

Photosensitizer-driven nanoassemblies of homodimeric prodrug for self-enhancing activation and synergistic chemo-photodynamic therapy
por: Zhang, Shenwu, et al.
Publicado: (2021)

Self-assembled organic nanorods for dual chemo-photodynamic therapies
por: Li, Yuanyuan, et al.
Publicado: (2018)

Photoactivation of Chemotherapeutic Agents with Cerenkov Radiation for Chemo-Photodynamic Therapy
por: Gallaga-González, Uriel, et al.
Publicado: (2022)

The Roles of Exosomes in Ovarian Cancer Chemo-resistance
por: Liu, Yang, et al.
Publicado: (2023)

Reduction-responsive worm-like nanoparticles for synergistic cancer chemo-photodynamic therapy
por: Hu, Hang, et al.
Publicado: (2023)

The microneedles carrying cisplatin and IR820 to perform synergistic chemo-photodynamic therapy against breast cancer
por: Fu, Ji-jun, et al.
Publicado: (2020)

Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy
por: Lin, Xiongjie, et al.
Publicado: (2022)

Multifunctional nanoplatforms as cascade-responsive drug-delivery carriers for effective synergistic chemo-photodynamic cancer treatment
por: Li, Fan, et al.
Publicado: (2021)

Stent Selection in Preoperative Biliary Drainage for Patients With Operable Pancreatic Cancer Receiving Neoadjuvant Therapy: A Meta-Analysis and Systematic Review
por: Du, Jianbing, et al.
Publicado: (2022)

Synergy of Chemo- and Photodynamic Therapies with C(60) Fullerene-Doxorubicin Nanocomplex
por: Grebinyk, Anna, et al.
Publicado: (2019)

Cell membranes targeted unimolecular prodrug for programmatic photodynamic-chemo therapy
por: Yuan, Jie, et al.
Publicado: (2021)

Enzyme and Reactive Oxygen Species–Responsive Dual-Drug Delivery Nanocomplex for Tumor Chemo-Photodynamic Therapy
por: Xie, Qian, et al.
Publicado: (2023)

Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma
por: Li, Xiaoju, et al.
Publicado: (2022)

Ultrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes
por: Guo, Yitong, et al.
Publicado: (2021)

Tumor Targeting Chemo- and Photodynamic Therapy Packaged in Albumin for Enhanced Anti-Tumor Efficacy
por: Zheng, Ke, et al.
Publicado: (2020)

Tumor Exosome Mimicking Nanoparticles for Tumor Combinatorial Chemo-Photothermal Therapy
por: Tian, Ran, et al.
Publicado: (2020)

Fluorescent Imaging-Guided Chemo- and Photodynamic Therapy of Hepatocellular Carcinoma with HCPT@NMOFs-RGD Nanocomposites
por: Shang, Yue, et al.
Publicado: (2022)

Photodynamic Therapy Combined with Ferroptosis Is a Synergistic Antitumor Therapy Strategy
por: Huang, Yunpeng, et al.
Publicado: (2023)

Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy
por: Weiss, Andrea, et al.
Publicado: (2015)

Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
por: Pandya, Abhilash D., et al.
Publicado: (2020)

Dual-Activated Nano-Prodrug for Chemo-Photodynamic Combination Therapy of Breast Cancer
por: Lu, Ziyao, et al.
Publicado: (2022)

pH-Responsive Nano-transferosomes of Purpurin-18 Sodium Salt and Doxorubicin for Enhanced Anticancer Efficiency by Photodynamic and Chemo Combination Therapy
por: Yeo, Sooho, et al.
Publicado: (2023)

Dual-responsive nanoparticles with transformable shape and reversible charge for amplified chemo-photodynamic therapy of breast cancer
por: Jia, Wenfeng, et al.
Publicado: (2022)

GSH-sensitive polymeric prodrug: Synthesis and loading with photosensitizers as nanoscale chemo-photodynamic anti-cancer nanomedicine
por: Luo, Lei, et al.
Publicado: (2022)

Pt(IV) prodrug initiated microparticles from microfluidics for tumor chemo-, photothermal and photodynamic combination therapy
por: Zhang, Qingfei, et al.
Publicado: (2022)

Lovastatin Inhibits Cancer Stem Cells and Sensitizes to Chemo- and Photodynamic Therapy in Nasopharyngeal Carcinoma
por: Peng, Yikun, et al.
Publicado: (2017)

Guiding Appropriate Timing of Laser Irradiation by Polymeric Micelles for Maximizing Chemo-Photodynamic Therapy
por: Zhu, Yun, et al.
Publicado: (2020)

Lipoparticles for Synergistic Chemo-Photodynamic Therapy to Ovarian Carcinoma Cells: In vitro and in vivo Assessments
por: Ali, Sajid, et al.
Publicado: (2021)

Evaluation of histone deacetylase inhibitor substituted zinc and indium phthalocyanines for chemo- and photodynamic therapy
por: Aru, Başak, et al.
Publicado: (2021)

3D CNT/MXene microspheres for combined photothermal/photodynamic/chemo for cancer treatment
por: Gao, Wei, et al.
Publicado: (2022)

Engineered Mesoporous Silica-Based Core-Shell Nanoarchitectures for Synergistic Chemo-Photodynamic Therapies
por: Gao, Yue-Mei, et al.
Publicado: (2022)

Glycosylated BODIPY- Incorporated Pt(II) Metallacycles for Targeted and Synergistic Chemo-Photodynamic Therapy
por: Durán-Sampedro, Gonzalo, et al.
Publicado: (2023)

Phospholipid membrane-decorated deep-penetrated nanocatalase relieve tumor hypoxia to enhance chemo-photodynamic therapy
por: Yin, Junjing, et al.
Publicado: (2020)

Ferroptosis resistance mediated by exosomal release of iron
por: Brown, Caitlin W., et al.
Publicado: (2020)

CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
por: Zhang, Haiyang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9h91eorp6bqf7aa5q5tq3nks1n