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The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare

INTRODUCTION: A C5 polymorphism (rs17611, 2404G>A) exists where the G allele associates with enhanced C5a-like production by neutrophil elastase. This cohort study investigated the influence of this polymorphism as a risk factor for lupus nephritis (LN), and on C5a and membrane attack complex (MA...

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Detalles Bibliográficos
Autores principales:	Toy, Chris R., Song, Huijuan, Nagaraja, Haikady N., Scott, Julia, Greco, Jessica, Zhang, Xiaolan, Yu, Chack-Yung, Tumlin, James A., Rovin, Brad H., Hebert, Lee A., Birmingham, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344111/ https://www.ncbi.nlm.nih.gov/pubmed/34386659 http://dx.doi.org/10.1016/j.ekir.2021.05.029

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