Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells

BACKGROUND: Ribosomal L1 domain-containing protein 1 (RSL1D1) is a nucleolar protein that is essential in cell proliferation. In the current opinion, RSL1D1 translocates to the nucleoplasm under nucleolar stress and inhibits the E3 ligase activity of HDM2 via direct interaction, thereby leading to s...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Li, Zhang, Zhiping, Zhao, Chenhong, Chen, Lei, Chen, Zhiqiang, Zhang, Jie, Liu, Yaxian, Nie, Yesen, He, Yanzhi, Liao, Kai, Zhang, Xinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344204/
https://www.ncbi.nlm.nih.gov/pubmed/34362424
http://dx.doi.org/10.1186/s13046-021-02057-8

Ejemplares similares

Ejemplares similares