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α-Amylase and dipeptidyl peptidase-4 (DPP-4) inhibitory effects of Melicope latifolia bark extracts and identification of bioactive constituents using in vitro and in silico approaches

CONTEXT: Melicope latifolia (DC.) T. G. Hartley (Rutaceae) was reported to contain various phytochemicals including coumarins, flavonoids, and acetophenones. OBJECTIVE: This study investigates the antidiabetic and antioxidant effects of M. latifolia bark extracts, fractions, and isolated constituent...

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Detalles Bibliográficos
Autores principales: Quek, Alexandra, Kassim, Nur Kartinee, Lim, Pei Cee, Tan, Dai Chuan, Mohammad Latif, Muhammad Alif, Ismail, Amin, Shaari, Khozirah, Awang, Khalijah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344235/
https://www.ncbi.nlm.nih.gov/pubmed/34347568
http://dx.doi.org/10.1080/13880209.2021.1948065