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Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)

Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twent...

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Autores principales: Roe, Chandler C., Urbanz, Jennifer, Andrews, Lela, Verocai, Guilherme G., Engelthaler, David M., Hepp, Crystal M., Sahl, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344259/
https://www.ncbi.nlm.nih.gov/pubmed/34377832
http://dx.doi.org/10.1080/23802359.2021.1960211
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author Roe, Chandler C.
Urbanz, Jennifer
Andrews, Lela
Verocai, Guilherme G.
Engelthaler, David M.
Hepp, Crystal M.
Sahl, Jason W.
author_facet Roe, Chandler C.
Urbanz, Jennifer
Andrews, Lela
Verocai, Guilherme G.
Engelthaler, David M.
Hepp, Crystal M.
Sahl, Jason W.
author_sort Roe, Chandler C.
collection PubMed
description Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an O. lupi isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related Onchocerca species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes.
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spelling pubmed-83442592021-08-09 Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) Roe, Chandler C. Urbanz, Jennifer Andrews, Lela Verocai, Guilherme G. Engelthaler, David M. Hepp, Crystal M. Sahl, Jason W. Mitochondrial DNA B Resour Mitogenome Announcement Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an O. lupi isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related Onchocerca species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes. Taylor & Francis 2021-08-05 /pmc/articles/PMC8344259/ /pubmed/34377832 http://dx.doi.org/10.1080/23802359.2021.1960211 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Mitogenome Announcement
Roe, Chandler C.
Urbanz, Jennifer
Andrews, Lela
Verocai, Guilherme G.
Engelthaler, David M.
Hepp, Crystal M.
Sahl, Jason W.
Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
title Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
title_full Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
title_fullStr Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
title_full_unstemmed Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
title_short Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
title_sort complete mitochondrial genome of onchocerca lupi (nematoda, onchocercidae)
topic Mitogenome Announcement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344259/
https://www.ncbi.nlm.nih.gov/pubmed/34377832
http://dx.doi.org/10.1080/23802359.2021.1960211
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