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Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twent...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344259/ https://www.ncbi.nlm.nih.gov/pubmed/34377832 http://dx.doi.org/10.1080/23802359.2021.1960211 |
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author | Roe, Chandler C. Urbanz, Jennifer Andrews, Lela Verocai, Guilherme G. Engelthaler, David M. Hepp, Crystal M. Sahl, Jason W. |
author_facet | Roe, Chandler C. Urbanz, Jennifer Andrews, Lela Verocai, Guilherme G. Engelthaler, David M. Hepp, Crystal M. Sahl, Jason W. |
author_sort | Roe, Chandler C. |
collection | PubMed |
description | Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an O. lupi isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related Onchocerca species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes. |
format | Online Article Text |
id | pubmed-8344259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-83442592021-08-09 Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) Roe, Chandler C. Urbanz, Jennifer Andrews, Lela Verocai, Guilherme G. Engelthaler, David M. Hepp, Crystal M. Sahl, Jason W. Mitochondrial DNA B Resour Mitogenome Announcement Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an O. lupi isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related Onchocerca species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes. Taylor & Francis 2021-08-05 /pmc/articles/PMC8344259/ /pubmed/34377832 http://dx.doi.org/10.1080/23802359.2021.1960211 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Mitogenome Announcement Roe, Chandler C. Urbanz, Jennifer Andrews, Lela Verocai, Guilherme G. Engelthaler, David M. Hepp, Crystal M. Sahl, Jason W. Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) |
title | Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) |
title_full | Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) |
title_fullStr | Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) |
title_full_unstemmed | Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) |
title_short | Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae) |
title_sort | complete mitochondrial genome of onchocerca lupi (nematoda, onchocercidae) |
topic | Mitogenome Announcement |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344259/ https://www.ncbi.nlm.nih.gov/pubmed/34377832 http://dx.doi.org/10.1080/23802359.2021.1960211 |
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