Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report

A 55-year-old man with hypogammaglobulinemia due to previous rituximab treatment developed persistent coronavirus disease 2019 pneumonia. Treatment with REGN-COV2 (casirivimab and imdevimab) resulted in the clearance of the infection. Targeted antiviral antibodies may be an important weapon in the m...

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Autores principales: Luitel, Pankaj, Vais, Dana, Gidron, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344477/
https://www.ncbi.nlm.nih.gov/pubmed/34405092
http://dx.doi.org/10.1093/ofid/ofab335
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author Luitel, Pankaj
Vais, Dana
Gidron, Adi
author_facet Luitel, Pankaj
Vais, Dana
Gidron, Adi
author_sort Luitel, Pankaj
collection PubMed
description A 55-year-old man with hypogammaglobulinemia due to previous rituximab treatment developed persistent coronavirus disease 2019 pneumonia. Treatment with REGN-COV2 (casirivimab and imdevimab) resulted in the clearance of the infection. Targeted antiviral antibodies may be an important weapon in the management of immunocompromised patients infected with severe acute respiratory syndrome coronavirus 2 who fail to mount an immune response.
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spelling pubmed-83444772021-08-10 Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report Luitel, Pankaj Vais, Dana Gidron, Adi Open Forum Infect Dis Brief Reports A 55-year-old man with hypogammaglobulinemia due to previous rituximab treatment developed persistent coronavirus disease 2019 pneumonia. Treatment with REGN-COV2 (casirivimab and imdevimab) resulted in the clearance of the infection. Targeted antiviral antibodies may be an important weapon in the management of immunocompromised patients infected with severe acute respiratory syndrome coronavirus 2 who fail to mount an immune response. Oxford University Press 2021-06-24 /pmc/articles/PMC8344477/ /pubmed/34405092 http://dx.doi.org/10.1093/ofid/ofab335 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Luitel, Pankaj
Vais, Dana
Gidron, Adi
Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report
title Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report
title_full Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report
title_fullStr Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report
title_full_unstemmed Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report
title_short Successful Treatment of Persistent Coronavirus Disease 2019 Infection in a Patient With Hypogammaglobulinemia With REGN-COV2: A Case Report
title_sort successful treatment of persistent coronavirus disease 2019 infection in a patient with hypogammaglobulinemia with regn-cov2: a case report
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344477/
https://www.ncbi.nlm.nih.gov/pubmed/34405092
http://dx.doi.org/10.1093/ofid/ofab335
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AT gidronadi successfultreatmentofpersistentcoronavirusdisease2019infectioninapatientwithhypogammaglobulinemiawithregncov2acasereport

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