Cargando…

Host cell protein detection gap risk mitigation: quantitative IAC-MS for ELISA antibody reagent coverage determination

Host cell proteins (HCPs) must be sufficiently cleared from recombinant biopharmaceuticals during the downstream process (DSP) to ensure product quality, purity, and patient safety. For monitoring of HCP clearance, the typical method chosen is an enzyme-linked immunosorbent assay (ELISA) using polyc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Waldera-Lupa, Daniel M., Jasper, Yvonne, Köhne, Pia, Schwichtenhövel, Ronja, Falkenberg, Heiner, Flad, Thomas, Happersberger, Peter, Reisinger, Bernd, Dehghani, Alireza, Moussa, Roland, Waerner, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344763/ https://www.ncbi.nlm.nih.gov/pubmed/34347561 http://dx.doi.org/10.1080/19420862.2021.1955432

Ejemplares similares

ELISA reagent coverage evaluation by affinity purification tandem mass spectrometry
por: Henry, Scott M., et al.
Publicado: (2017)

ESO-IAC Conference on Quasar Hosts
por: Clements, D, et al.
Publicado: (1997)

IAC Winter School on Galaxy Formation and Evolution
por: Muñoz-Tunón, C
Publicado: (1993)

Proteome-wide analysis of in situ aged fibroblasts
por: Waldera-Lupa, Daniel M., et al.
Publicado: (2015)

6th IAC Winter School : the Structure of the Sun
por: Roca Cortes, T
Publicado: (1995)

ING-IAC Joint Conference on Satellites And Tidal Streams
Publicado: (2003)

2nd IAC Winter School on Observational and Physical Cosmology
Publicado: (1990)

Benchmarking alcohol policy based on stringency and impact: The International Alcohol Control (IAC) policy index
por: Casswell, Sally, et al.
Publicado: (2022)

Prevalence of renal dysfunction in patients with cirrhosis according to ADQI-IAC working party proposal
por: Choi, Yun Jung, et al.
Publicado: (2014)

Intersection and Complement Set (IACS) Method to Reduce Redundant Node in Mobile WSN Localization
por: Mohd. Zaid Harith, Muhammad Zar, et al.
Publicado: (2018)

OutCyte: a novel tool for predicting unconventional protein secretion
por: Zhao, Linlin, et al.
Publicado: (2019)

Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells
por: Vangapandu, Hima V., et al.
Publicado: (2018)

Prognostic Stratification of Multiple Myeloma Using Clinicogenomic Models: Validation and Performance Analysis of the IAC-50 Model
por: Mosquera Orgueira, Adrián, et al.
Publicado: (2022)

Correction: Benchmarking alcohol policy based on stringency and impact: The International Alcohol Control (IAC) Policy Index
Publicado: (2022)

Double antibody pairs sandwich-ELISA (DAPS-ELISA) detects Acidovorax citrulli serotypes with broad coverage
por: Himananto, Orawan, et al.
Publicado: (2020)

FNAC of Breast Lesions with Special Reference to IAC Standardized Reporting and Comparative Study of Cytohistological Grading of Breast Carcinoma
por: Panwar, Hemlata, et al.
Publicado: (2020)

The role of laboratory medicine in healthcare: quality requirements of immunoassays, standardisation and data management in prospective medicine
por: Waerner, Thomas, et al.
Publicado: (2010)

Biotin-tagged proteins: Reagents for efficient ELISA-based serodiagnosis and phage display-based affinity selection
por: Verma, Vaishali, et al.
Publicado: (2018)

Risk of Malignancy in Breast FNAB Categories, Classified According to the Newly Proposed International Academy of Cytology (IAC) Yokohama System
por: Niaz, Mahwish, et al.
Publicado: (2022)

Proteomic changes in cerebrospinal fluid from primary central nervous system lymphoma patients are associated with protein ectodomain shedding
por: Waldera-Lupa, Daniel Michael, et al.
Publicado: (2017)

A novel approach to evaluate ELISA antibody coverage of host cell proteins—combining ELISA‐based immunocapture and mass spectrometry
por: Pilely, Katrine, et al.
Publicado: (2020)

Infrastructure as code (IAC) cookbook: over 90 practical, actionable recipes to automate, test and manage your infrastructure quickly and effectively
por: Jourdan, Stephane, et al.
Publicado: (2017)

Analysis of clinical characteristics and treatment of immunoglobulin G4-associated cholangitis: A retrospective cohort study of 39 IAC patients
por: Xiao, Jianchun, et al.
Publicado: (2018)

Detection of histidine rich protein & lactate dehydrogenase of Plasmodium falciparum in malaria patients by sandwich ELISA using in-house reagents
por: Verma, Priyanka, et al.
Publicado: (2013)

1726. Candida albicans Virulence Genes Induced During Intra-abdominal Candidiasis (IAC) in the Absence of Antifungal Exposure Mediate Echinocandin Resistance
por: Clancy, Cornelius J, et al.
Publicado: (2019)

2887. Identifying Candida albicans Transcription Factors (TFs) That Regulate Pathogenesis of Intra-abdominal Candidiasis (IAC) by Screening a Deletion Mutant Library
por: Clancy, Cornelius J, et al.
Publicado: (2019)

IAC方案治疗复发/难治急性髓系白血病疗效与安全性分析：前瞻性随机对照研究
Publicado: (2022)

Characteristics, Quality, and Safety Issues Identified During Intersocietal Accreditation Commission (IAC) Assessment of Orthopaedic Facilities Utilizing Cone-Beam CT Equipment
por: Farrell, Mary B., et al.
Publicado: (2022)

Low HIV viral suppression rates following the intensive adherence counseling (IAC) program for children and adolescents with viral failure in public health facilities in Uganda
por: Nasuuna, Esther, et al.
Publicado: (2018)

K205R specific nanobody-horseradish peroxidase fusions as reagents of competitive ELISA to detect African swine fever virus serum antibodies
por: Zhang, Angke, et al.
Publicado: (2022)

Rediscovering Sulfinylamines as Reagents for Organic Synthesis
por: Davies, Thomas Q., et al.
Publicado: (2021)

Characteristics and Predictors of Heavy Episodic Drinking (HED) among Young People Aged 16–25: The International Alcohol Control Study (IAC), Tshwane, South Africa
por: Harker, Nadine, et al.
Publicado: (2020)

Negishi's Reagent Versus Rosenthal's Reagent in the Formation of Zirconacyclopentadienes
por: Urrego‐Riveros, Sara, et al.
Publicado: (2019)

Thioamination of Alkenes with Hypervalent Iodine Reagents
por: Mizar, Pushpak, et al.
Publicado: (2016)

Borane reagents /
por: Pelter, Andrew
Publicado: (1988)

Larvicidal Reagents
por: Sprawson, C. A.
Publicado: (1901)

A Multiplex Assay for the Stratification of Patients with Primary Central Nervous System Lymphoma Using Targeted Mass Spectrometry
por: Waldera-Lupa, Daniel M., et al.
Publicado: (2020)

Direct synthesis and applications of solid silylzinc reagents
por: Chandrasekaran, Revathi, et al.
Publicado: (2021)

The Combined Treatment With the FLT3-Inhibitor AC220 and the Complex I Inhibitor IACS-010759 Synergistically Depletes Wt- and FLT3-Mutated Acute Myeloid Leukemia Cells
por: Lu, Xiyuan, et al.
Publicado: (2021)

Photons as a 21st century reagent
por: Bonfield, Holly E., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s3c05jrhgb1osqvirtkuq0fqrs