Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway

Septic cardiomyopathy is a common complication of severe sepsis, which is one of the leading causes of death in intensive care units. Therefore, finding an effective therapy target is urgent. Neferine is an alkaloid extracted from the green embryos of mature seeds of Nelumbo nucifera Gaertn., which...

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Detalles Bibliográficos
Autores principales: Qi, Zhen, Wang, Renrong, Liao, Rongheng, Xue, Song, Wang, Yongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344844/
https://www.ncbi.nlm.nih.gov/pubmed/34366860
http://dx.doi.org/10.3389/fphar.2021.706251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344844/
https://www.ncbi.nlm.nih.gov/pubmed/34366860
http://dx.doi.org/10.3389/fphar.2021.706251

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