Cargando…

Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response

Planarians are able to stand long periods of starvation by maintaining adult stem cell pools and regenerative capacity. The molecular pathways that are needed for the maintenance of regeneration during starvation are not known. Here, we show that down‐regulation of chaperonin TRiC/CCT subunits abrog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gutiérrez‐Gutiérrez, Óscar, Felix, Daniel A, Salvetti, Alessandra, Amro, Elias M, Thems, Anne, Pietsch, Stefan, Koeberle, Andreas, Rudolph, K Lenhard, González‐Estévez, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344900/ https://www.ncbi.nlm.nih.gov/pubmed/34190393 http://dx.doi.org/10.15252/embr.202152905

Ejemplares similares

Functional Subunits of Eukaryotic Chaperonin CCT/TRiC in Protein Folding
por: Kabir, M. Anaul, et al.
Publicado: (2011)

Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex
por: Génier, Samuel, et al.
Publicado: (2016)

Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy
por: Pereira, Jose H., et al.
Publicado: (2017)

Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT
por: Booth, Christopher R, et al.
Publicado: (2008)

The Cytosolic Chaperonin CCT/TRiC and Cancer Cell Proliferation
por: Boudiaf-Benmammar, Chafika, et al.
Publicado: (2013)

Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis
por: Roh, Soung-Hun, et al.
Publicado: (2015)

Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin
por: Kasembeli, Moses, et al.
Publicado: (2014)

Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila
por: Ohhara, Yuya, et al.
Publicado: (2019)

Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC
por: Yamamoto, Yohei Y., et al.
Publicado: (2017)

Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT
por: Date, Yuki, et al.
Publicado: (2022)

Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT
por: Han, Wenyu, et al.
Publicado: (2023)

TRiC/CCT chaperonin is required for the folding and inhibitory effect of WDTC1 on adipogenesis
por: Tang, Wen-Shuai, et al.
Publicado: (2023)

TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila
por: Kim, Ah-Ram, et al.
Publicado: (2019)

Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns
por: Collier, Miranda P., et al.
Publicado: (2021)

Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT
por: Zang, Yunxiang, et al.
Publicado: (2018)

The Molecular Chaperone CCT/TRiC: An Essential Component of Proteostasis and a Potential Modulator of Protein Aggregation
por: Grantham, Julie
Publicado: (2020)

Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma
por: Cox, Amanda, et al.
Publicado: (2022)

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly-made proteins with complex topologies
por: Yam, Alice Y., et al.
Publicado: (2008)

Recognition of the CCT5 di‐Glu degron by CRL4(DCAF12) is dependent on TRiC assembly
por: Pla‐Prats, Carlos, et al.
Publicado: (2023)

Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells
por: Saegusa, Keiko, et al.
Publicado: (2014)

State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps
por: Zhang, Yan, et al.
Publicado: (2020)

Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM
por: Liu, Caixuan, et al.
Publicado: (2023)

Molecular Dynamics Mappings of the CCT/TRiC Complex-Mediated Protein Folding Cycle Using Diffracted X-ray Tracking
por: Araki, Kazutaka, et al.
Publicado: (2023)

The TRiC/CCT Chaperone Is Implicated in Alzheimer's Disease Based on Patient GWAS and an RNAi Screen in Aβ-Expressing Caenorhabditis elegans
por: Khabirova, Eleonora, et al.
Publicado: (2014)

TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes
por: Wang, Yuchen, et al.
Publicado: (2020)

TRiC’s tricks inhibit huntingtin aggregation
por: Shahmoradian, Sarah H, et al.
Publicado: (2013)

An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity
por: Jin, Mingliang, et al.
Publicado: (2019)

Systematic Characterization of Expression Profiles and Prognostic Values of the Eight Subunits of the Chaperonin TRiC in Breast Cancer
por: Xu, Wen-Xiu, et al.
Publicado: (2021)

Involvement of T-complex protein 1-ring complex/chaperonin containing T-complex protein 1 (TRiC/CCT) in retrograde axonal transport through tau phosphorylation
por: Chen, Xu-Qiao
Publicado: (2019)

Snapshots of actin and tubulin folding inside the TRiC chaperonin
por: Kelly, John J., et al.
Publicado: (2022)

The Role of TRiC-enhanced Actin Folding in Leber Congenital Amaurosis
por: Berger, Silke, et al.
Publicado: (2023)

Usher syndrome proteins ADGRV1 (USH2C) and CIB2 (USH1J) interact and share a common interactome containing TRiC/CCT-BBS chaperonins
por: Linnert, Joshua, et al.
Publicado: (2023)

The TRiC Chaperonin Controls Reovirus Replication through Outer-Capsid Folding
por: Knowlton, Jonathan J., et al.
Publicado: (2018)

CCTα and CCTδ Chaperonin Subunits Are Essential and Required for Cilia Assembly and Maintenance in Tetrahymena
por: Seixas, Cecilia, et al.
Publicado: (2010)

The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2
por: Hu, Jianshu, et al.
Publicado: (2023)

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A
por: Pines, Alex, et al.
Publicado: (2018)

Mob4-dependent STRIPAK involves the chaperonin TRiC to coordinate myofibril and microtubule network growth
por: Berger, Joachim, et al.
Publicado: (2022)

An insight into planarian regeneration
por: Ge, Xin‐Yang, et al.
Publicado: (2022)

Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle
por: Cong, Yao, et al.
Publicado: (2012)

Starving
Publicado: (1890)

Cannot write session to /tmp/vufind_sessions/sess_24djjq0dbgrog293av4r42n49i