Residual pluripotency is required for inductive germ cell segregation

Fine‐tuned dissolution of pluripotency is critical for proper cell differentiation. Here we show that the mesodermal transcription factor, T, globally affects the properties of pluripotency through binding to Oct4 and to the loci of other pluripotency regulators. Strikingly, lower T levels coordinat...

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Detalles Bibliográficos
Autores principales: Aramaki, Shinya, Kagiwada, Saya, Wu, Guangming, Obridge, David, Adachi, Kenjiro, Kutejova, Eva, Lickert, Heiko, Hübner, Karin, Schöler, Hans R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344911/
https://www.ncbi.nlm.nih.gov/pubmed/34156139
http://dx.doi.org/10.15252/embr.202152553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344911/
https://www.ncbi.nlm.nih.gov/pubmed/34156139
http://dx.doi.org/10.15252/embr.202152553

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