Cargando…

Residual pluripotency is required for inductive germ cell segregation

Fine‐tuned dissolution of pluripotency is critical for proper cell differentiation. Here we show that the mesodermal transcription factor, T, globally affects the properties of pluripotency through binding to Oct4 and to the loci of other pluripotency regulators. Strikingly, lower T levels coordinat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aramaki, Shinya, Kagiwada, Saya, Wu, Guangming, Obridge, David, Adachi, Kenjiro, Kutejova, Eva, Lickert, Heiko, Hübner, Karin, Schöler, Hans R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344911/ https://www.ncbi.nlm.nih.gov/pubmed/34156139 http://dx.doi.org/10.15252/embr.202152553

Ejemplares similares

YAP establishes epiblast responsiveness to inductive signals for germ cell fate
por: Kagiwada, Saya, et al.
Publicado: (2021)

Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile
por: Sugawa, Fumihiro, et al.
Publicado: (2015)

Induction of Primordial Germ Cells from Pluripotent Epiblast
por: Ying, Ying, et al.
Publicado: (2002)

Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency
por: Tiemann, Ulf, et al.
Publicado: (2014)

Advances in Female Germ Cell Induction from Pluripotent Stem Cells
por: Gulimiheranmu, Maisumu, et al.
Publicado: (2021)

Induction of pluripotency by defined factors
por: TANABE, Koji, et al.
Publicado: (2014)

A balanced Oct4 interactome is crucial for maintaining pluripotency
por: Han, Dong, et al.
Publicado: (2022)

Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells
por: Wang, Hanning, et al.
Publicado: (2016)

Germ Cell Nuclear Factor Regulates Gametogenesis in Developing Gonads
por: Sabour, Davood, et al.
Publicado: (2014)

Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development
por: Strasser, Markus J, et al.
Publicado: (2008)

Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause
por: Fan, Rui, et al.
Publicado: (2020)

A Dynamic Role of TBX3 in the Pluripotency Circuitry
por: Russell, Ronan, et al.
Publicado: (2015)

Rebuilding Pluripotency from Primordial Germ Cells
por: Leitch, Harry G., et al.
Publicado: (2013)

The Germ Cell Determinant Blimp1 Is Not Required for Derivation of Pluripotent Stem Cells
por: Bao, Siqin, et al.
Publicado: (2012)

SOX17 links gut endoderm morphogenesis with germ layer segregation
por: Viotti, Manuel, et al.
Publicado: (2014)

Evaluation of the determinants for improved pluripotency induction and maintenance by engineered SOX17
por: Hu, Haoqing, et al.
Publicado: (2023)

Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
por: Xiong, Le, et al.
Publicado: (2022)

Expression, sorting, and segregation of Golgi proteins during germ cell differentiation in the testis
por: Au, Catherine E., et al.
Publicado: (2015)

Reprogramming Primordial Germ Cells into Pluripotent Stem Cells
por: Durcova-Hills, Gabriela, et al.
Publicado: (2008)

Differential Expression of Conserved Germ Line Markers and Delayed Segregation of Male and Female Primordial Germ Cells in a Hermaphrodite, the Leech Helobdella
por: Cho, Sung-Jin, et al.
Publicado: (2014)

Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs
por: Velychko, Sergiy, et al.
Publicado: (2019)

Regulation of germ layer formation by pluripotency factors during embryogenesis
por: Cao, Ying
Publicado: (2013)

Generation of germ cells from pluripotent stem cells in mammals
por: Hayashi, Masafumi, et al.
Publicado: (2017)

Differentiation of Induced Pluripotent Stem Cells into Male Germ Cells In Vitro through Embryoid Body Formation and Retinoic Acid or Testosterone Induction
por: Li, Peng, et al.
Publicado: (2013)

Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells
por: Fang, Fang, et al.
Publicado: (2020)

BRG1 Is Required to Maintain Pluripotency of Murine Embryonic Stem Cells
por: Singhal, Nishant, et al.
Publicado: (2014)

The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells
por: Okumura, Leah M., et al.
Publicado: (2013)

A pluripotent developmental state confers a low fidelity of chromosome segregation
por: Deng, Chenhui, et al.
Publicado: (2023)

DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells
por: Chen, Hsu-Hsin, et al.
Publicado: (2014)

Tracing the transitions from pluripotency to germ cell fate with CRISPR screening
por: Hackett, Jamie A., et al.
Publicado: (2018)

Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate
por: Tischler, Julia, et al.
Publicado: (2018)

Neonatal Porcine Germ Cells Dedifferentiate and Display Osteogenic and Pluripotency Properties
por: Fayaz, Mohammad Amin, et al.
Publicado: (2021)

The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells
por: Wang, Xiaoman, et al.
Publicado: (2021)

Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming
por: Marthaler, Adele G., et al.
Publicado: (2016)

Expression of Genes Related to Germ Cell Lineage and Pluripotency in Single Cells and Colonies of Human Adult Germ Stem Cells
por: Conrad, Sabine, et al.
Publicado: (2016)

Nodal and churchill1 position the expression of a notch ligand during Xenopus germ layer segregation
por: Favarolo, María Belén, et al.
Publicado: (2022)

Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate
por: Marthaler, Adele G., et al.
Publicado: (2013)

Tuberculosis in postchemotherapy residual masses in germ cell tumor of the testis
por: Bansal, Rajesh, et al.
Publicado: (2011)

Homogeneity of XEN Cells Is Critical for Generation of Chemically Induced Pluripotent Stem Cells
por: Jeong, Dahee, et al.
Publicado: (2023)

Tbx3 improves the germ-line competency of induced pluripotent stem cells
por: Han, Jianyong, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_8i35hl7hk4cr6s3v0lkru1eojn