Docetaxel Skin Exposure and Micronucleation Contributes to Skin Toxicity Caused by CPC634

SIMPLE SUMMARY: CPC634 is a nanoparticle entrapping docetaxel that is associated with skin toxicity that resembles conventional docetaxel-related skin toxicity. In this randomised cross-over study, the cutaneous pharmacokinetics and pharmacodynamics of docetaxel and CPC634 were compared to unravel t...

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Detalles Bibliográficos
Autores principales: Atrafi, Florence, van Eerden, Ruben A. G., Koolen, Stijn L. W., de Bruijn, Peter, Rijcken, Cristianne J. F., Hanssen, Rob, Eskens, Ferry A. L. M., Lolkema, Martijn P., Oomen-de Hoop, Esther, Damman, Jeffrey, Mathijssen, Ron H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345028/
https://www.ncbi.nlm.nih.gov/pubmed/34359641
http://dx.doi.org/10.3390/cancers13153741

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