Involvement of HIF-1α in the Detection, Signaling, and Repair of DNA Double-Strand Breaks after Photon and Carbon-Ion Irradiation

SIMPLE SUMMARY: Hypoxia-Inducible Factor 1α (HIF-1α), the main regulator of the oxygen homeostasis, promotes cancer cell survival through proliferation, angiogenesis, metastasis and radioresistance. Previously, our group demonstrated that silencing HIF-1α under hypoxia leads to a substantial radiose...

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Detalles Bibliográficos
Autores principales: Wozny, Anne-Sophie, Gauthier, Arnaud, Alphonse, Gersende, Malésys, Céline, Varoclier, Virginie, Beuve, Michael, Brichart-Vernos, Delphine, Magné, Nicolas, Vial, Nicolas, Ardail, Dominique, Nakajima, Tetsuo, Rodriguez-Lafrasse, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345054/
https://www.ncbi.nlm.nih.gov/pubmed/34359734
http://dx.doi.org/10.3390/cancers13153833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345054/
https://www.ncbi.nlm.nih.gov/pubmed/34359734
http://dx.doi.org/10.3390/cancers13153833

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