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A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor–Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy

SIMPLE SUMMARY: Mathematical and computational models, such as quantitative systems pharmacology (QSP) models, are becoming a popular tool in drug discovery. The advancement of imaging techniques creates a unique opportunity to further expand these models and enhance their predictive power by incorp...

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Detalles Bibliográficos
Autores principales: Gong, Chang, Ruiz-Martinez, Alvaro, Kimko, Holly, Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345161/
https://www.ncbi.nlm.nih.gov/pubmed/34359653
http://dx.doi.org/10.3390/cancers13153751