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Targeting RB1 Loss in Cancers

SIMPLE SUMMARY: Irreversible defects in RB1 tumor suppressor functions often predict poor outcomes in cancer patients. However, the RB1-defecient status can be a benefit as well for them, as it generates a variety of vulnerabilities induced through the upregulation of RB1 targets, relief from functi...

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Detalles Bibliográficos
Autores principales:	Linn, Paing, Kohno, Susumu, Sheng, Jindan, Kulathunga, Nilakshi, Yu, Hai, Zhang, Zhiheng, Voon, Dominic, Watanabe, Yoshihiro, Takahashi, Chiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345210/ https://www.ncbi.nlm.nih.gov/pubmed/34359636 http://dx.doi.org/10.3390/cancers13153737

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