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Clinical Significance of Telomerase Reverse-Transcriptase Promoter Mutations in Hepatocellular Carcinoma

SIMPLE SUMMARY: Activating mutations in the promoter region of TERT (TERTp) gene are frequently observed in low- and high-grade dysplastic nodules and defined as early events in hepatocellular carcinoma development. This study shows that the nucleotide change G>A at position −124 in the TERTp reg...

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Detalles Bibliográficos
Autores principales:	Pezzuto, Francesca, Izzo, Francesco, De Luca, Pasquale, Biffali, Elio, Buonaguro, Luigi, Tatangelo, Fabiana, Buonaguro, Franco Maria, Tornesello, Maria Lina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345216/ https://www.ncbi.nlm.nih.gov/pubmed/34359670 http://dx.doi.org/10.3390/cancers13153771

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