Cell-Extrinsic Differentiation Block Mediated by EphA3 in Pre-Leukaemic Thymus Contributes to Disease Progression

SIMPLE SUMMARY: The NUP98-HOXD13 (NHD13) mouse is a model of T-cell leukaemia (T-ALL) featuring a pre-leukemic phase, in which T-cell progenitors from the thymus of an NHD13 mouse can engraft into the thymus of a recipient mouse—an ability that normal T-cell progenitors do not possess. However, loss...

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Detalles Bibliográficos
Autores principales: Pliego Zamora, Adriana C., Ranasinghe, Hansini, Lisle, Jessica E., Ng, Chun Ki, Huang, Stephen, Wadlow, Racheal, Scott, Andrew M., Boyd, Andrew W., Slape, Christopher I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345401/
https://www.ncbi.nlm.nih.gov/pubmed/34359759
http://dx.doi.org/10.3390/cancers13153858

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