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Review of the Molecular Genetics of Basal Cell Carcinoma; Inherited Susceptibility, Somatic Mutations, and Targeted Therapeutics

SIMPLE SUMMARY: Basal cell carcinoma is the most common human cancer worldwide. The molecular basis of BCC involves an interplay of inherited genetic susceptibility and somatic mutations, commonly induced by exposure to UV radiation. In this review, we outline the currently known germline and somati...

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Detalles Bibliográficos
Autores principales: Kilgour, James M., Jia, Justin L., Sarin, Kavita Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345475/
https://www.ncbi.nlm.nih.gov/pubmed/34359772
http://dx.doi.org/10.3390/cancers13153870