Cargando…
Review of the Molecular Genetics of Basal Cell Carcinoma; Inherited Susceptibility, Somatic Mutations, and Targeted Therapeutics
SIMPLE SUMMARY: Basal cell carcinoma is the most common human cancer worldwide. The molecular basis of BCC involves an interplay of inherited genetic susceptibility and somatic mutations, commonly induced by exposure to UV radiation. In this review, we outline the currently known germline and somati...
Autores principales: | Kilgour, James M., Jia, Justin L., Sarin, Kavita Y. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345475/ https://www.ncbi.nlm.nih.gov/pubmed/34359772 http://dx.doi.org/10.3390/cancers13153870 |
Ejemplares similares
-
Inheritance of somatic mutations by animal offspring
por: Vasquez Kuntz, Kate L., et al.
Publicado: (2022) -
Rolling the genetic dice: neutral and deleterious Smoothened mutations in drug-resistant basal cell carcinoma
por: Atwood, Scott X., et al.
Publicado: (2015) -
Somatic mutations in salivary duct carcinoma and potential therapeutic targets
por: Khoo, Timothy K., et al.
Publicado: (2017) -
Coding and noncoding somatic mutations in candidate genes in basal cell carcinoma
por: Maturo, Maria Giovanna, et al.
Publicado: (2020) -
Inherited variants in genes somatically mutated in thyroid cancer
por: Campo, Chiara, et al.
Publicado: (2017)