Irreversible Electroporation and Nivolumab Combined with Intratumoral Administration of a Toll-Like Receptor Ligand, as a Means of In Vivo Vaccination for Metastatic Pancreatic Ductal Adenocarcinoma (PANFIRE-III). A Phase-I Study Protocol

SIMPLE SUMMARY: Metastatic pancreatic ductal adenocarcinoma has a dismal prognosis, and to date no curative treatment options exist. The image guided tumor ablation technique irreversible electroporation (IRE) employs high-voltage electrical pulses through the application of several needle electrode...

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Detalles Bibliográficos
Autores principales: Geboers, Bart, Timmer, Florentine E. F., Ruarus, Alette H., Pouw, Johanna E. E., Schouten, Evelien A. C., Bakker, Joyce, Puijk, Robbert S., Nieuwenhuizen, Sanne, Dijkstra, Madelon, van den Tol, M. Petrousjka, de Vries, Jan J. J., Oprea-Lager, Daniela E., Menke-van der Houven van Oordt, C. Willemien, van der Vliet, Hans J., Wilmink, Johanna W., Scheffer, Hester J., de Gruijl, Tanja D., Meijerink, Martijn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345515/
https://www.ncbi.nlm.nih.gov/pubmed/34359801
http://dx.doi.org/10.3390/cancers13153902

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