Adjustment for Baseline Covariates to Increase Efficiency in RCTs with Binary Endpoint: A Comparison of Bayesian and Frequentist Approaches

Background: In a randomized controlled trial (RCT) with binary outcome the estimate of the marginal treatment effect can be biased by prognostic baseline covariates adjustment. Methods that target the marginal odds ratio, allowing for improved precision and power, have been developed. Methods: The p...

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Detalles Bibliográficos
Autores principales: Berchialla, Paola, Sciannameo, Veronica, Urru, Sara, Lanera, Corrado, Azzolina, Danila, Gregori, Dario, Baldi, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345531/
https://www.ncbi.nlm.nih.gov/pubmed/34360051
http://dx.doi.org/10.3390/ijerph18157758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345531/
https://www.ncbi.nlm.nih.gov/pubmed/34360051
http://dx.doi.org/10.3390/ijerph18157758

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