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Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas

SIMPLE SUMMARY: Histological diagnoses within the spectrum from moderately dysplastic nevi to thin melanomas are neither accurate nor reproducible, emphasizing the need for more objective supplemental immunohistochemical markers. PRAME immunohistochemistry aids in differentiating unequivocal melanom...

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Detalles Bibliográficos
Autores principales: Gassenmaier, Maximilian, Hahn, Matthias, Metzler, Gisela, Bauer, Jürgen, Yazdi, Amir Sadegh, Keim, Ulrike, Garbe, Claus, Wagner, Nikolaus Benjamin, Forchhammer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345662/
https://www.ncbi.nlm.nih.gov/pubmed/34359765
http://dx.doi.org/10.3390/cancers13153864