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APLN/APLNR Signaling Controls Key Pathological Parameters of Glioblastoma

SIMPLE SUMMARY: The neurovascular peptide Apelin and its receptor APLNR are upregulated during glioblastoma pathology. Here we summarize their role in the brain tumor microenvironment composed of neurons, astrocytes, and the vascular and immune systems. Targeting APLN/APLNR signaling promises to unf...

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Detalles Bibliográficos
Autores principales:	Kälin, Roland E., Glass, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345670/ https://www.ncbi.nlm.nih.gov/pubmed/34359800 http://dx.doi.org/10.3390/cancers13153899

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