Cargando…

Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting

Breast cancer (BCa) and prostate cancer (PCa) are the most prevalent types of cancers. We aimed to understand and analyze the care pathways for BCa and PCa patients followed at a hospital setting by analyzing their different treatment lines. We evaluated the association between different treatment l...

Descripción completa

Detalles Bibliográficos
Autores principales: Bardhi, Ornela, Garcia-Zapirain, Begonya, Nuño-Solinis, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345796/
https://www.ncbi.nlm.nih.gov/pubmed/34360204
http://dx.doi.org/10.3390/ijerph18157913
_version_ 1783734715805597696
author Bardhi, Ornela
Garcia-Zapirain, Begonya
Nuño-Solinis, Roberto
author_facet Bardhi, Ornela
Garcia-Zapirain, Begonya
Nuño-Solinis, Roberto
author_sort Bardhi, Ornela
collection PubMed
description Breast cancer (BCa) and prostate cancer (PCa) are the most prevalent types of cancers. We aimed to understand and analyze the care pathways for BCa and PCa patients followed at a hospital setting by analyzing their different treatment lines. We evaluated the association between different treatment lines and the lifestyle and demographic characteristics of these patients. Two datasets were created using the electronic health records (EHRs) and information collected through semi-structured one-on-one interviews. Statistical analysis was performed to examine which variable had an impact on the treatment each patient followed. In total, 83 patients participated in the study that ran between January and November 2018 in Beacon Hospital. Results show that chemotherapy cycles indicate if a patient would have other treatments, i.e., patients who have targeted therapy (25/46) have more chemotherapy cycles (95% CI 4.66–9.52, p = 0.012), the same is observed with endocrine therapy (95% CI 4.77–13.59, p = 0.044). Patients who had bisphosphonate (11/46), an indication of bone metastasis, had more chemotherapy cycles (95% CI 5.19–6.60, p = 0.012). PCa patients with tall height (95% CI 176.70–183.85, p = 0.005), heavier (95% CI 85.80–99.57, p < 0.001), and a BMI above 25 (95% CI 1.85–2.62, p = 0.017) had chemotherapy compared to patients who were shorter, lighter and with BMI less than 25. Initial prostate-specific antigen level (PSA level) indicated if a patient would be treated with bisphosphonate or not (95% CI 45.51–96.14, p = 0.002). Lifestyle variables such as diet (95% CI 1.46–1.85, p = 0.016), and exercise (95% CI 1.20–1.96, p = 0.029) indicated that healthier and active BCa patients had undergone surgeries. Our findings show that chemotherapy cycles and lifestyle for BCa, and tallness and weight for PCa may indicate the rest of treatment plan for these patients. Understanding factors that influence care pathways allow a more person-centered care approach and the redesign of care processes.
format Online
Article
Text
id pubmed-8345796
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83457962021-08-07 Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting Bardhi, Ornela Garcia-Zapirain, Begonya Nuño-Solinis, Roberto Int J Environ Res Public Health Article Breast cancer (BCa) and prostate cancer (PCa) are the most prevalent types of cancers. We aimed to understand and analyze the care pathways for BCa and PCa patients followed at a hospital setting by analyzing their different treatment lines. We evaluated the association between different treatment lines and the lifestyle and demographic characteristics of these patients. Two datasets were created using the electronic health records (EHRs) and information collected through semi-structured one-on-one interviews. Statistical analysis was performed to examine which variable had an impact on the treatment each patient followed. In total, 83 patients participated in the study that ran between January and November 2018 in Beacon Hospital. Results show that chemotherapy cycles indicate if a patient would have other treatments, i.e., patients who have targeted therapy (25/46) have more chemotherapy cycles (95% CI 4.66–9.52, p = 0.012), the same is observed with endocrine therapy (95% CI 4.77–13.59, p = 0.044). Patients who had bisphosphonate (11/46), an indication of bone metastasis, had more chemotherapy cycles (95% CI 5.19–6.60, p = 0.012). PCa patients with tall height (95% CI 176.70–183.85, p = 0.005), heavier (95% CI 85.80–99.57, p < 0.001), and a BMI above 25 (95% CI 1.85–2.62, p = 0.017) had chemotherapy compared to patients who were shorter, lighter and with BMI less than 25. Initial prostate-specific antigen level (PSA level) indicated if a patient would be treated with bisphosphonate or not (95% CI 45.51–96.14, p = 0.002). Lifestyle variables such as diet (95% CI 1.46–1.85, p = 0.016), and exercise (95% CI 1.20–1.96, p = 0.029) indicated that healthier and active BCa patients had undergone surgeries. Our findings show that chemotherapy cycles and lifestyle for BCa, and tallness and weight for PCa may indicate the rest of treatment plan for these patients. Understanding factors that influence care pathways allow a more person-centered care approach and the redesign of care processes. MDPI 2021-07-26 /pmc/articles/PMC8345796/ /pubmed/34360204 http://dx.doi.org/10.3390/ijerph18157913 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bardhi, Ornela
Garcia-Zapirain, Begonya
Nuño-Solinis, Roberto
Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
title Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
title_full Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
title_fullStr Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
title_full_unstemmed Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
title_short Factors Influencing Care Pathways for Breast and Prostate Cancer in a Hospital Setting
title_sort factors influencing care pathways for breast and prostate cancer in a hospital setting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345796/
https://www.ncbi.nlm.nih.gov/pubmed/34360204
http://dx.doi.org/10.3390/ijerph18157913
work_keys_str_mv AT bardhiornela factorsinfluencingcarepathwaysforbreastandprostatecancerinahospitalsetting
AT garciazapirainbegonya factorsinfluencingcarepathwaysforbreastandprostatecancerinahospitalsetting
AT nunosolinisroberto factorsinfluencingcarepathwaysforbreastandprostatecancerinahospitalsetting