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Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching

The EuroTransplant Kidney Allocation System (ETKAS) aims at allocating organs to patients on the waiting list fairly whilst optimizing HLA match grades. ETKAS currently considers the number of HLA-A, -B, -DR mismatches. Evidently, epitope matching is biologically and clinically more relevant. We her...

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Detalles Bibliográficos
Autores principales:	Niemann, Matthias, Lachmann, Nils, Geneugelijk, Kirsten, Spierings, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345832/ https://www.ncbi.nlm.nih.gov/pubmed/34314431 http://dx.doi.org/10.1371/journal.pcbi.1009248

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