The bromodomain inhibitor JQ1+ reduces calcium-sensing receptor activity in pituitary cell lines

Corticotrophinomas represent 10% of all surgically removed pituitary adenomas, however, current treatment options are often not effective, and there is a need for improved pharmacological treatments. Recently, JQ1+, a bromodomain inhibitor that promotes gene transcription by binding acetylated histo...

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Detalles Bibliográficos
Autores principales: Lines, Kate E, Gluck, Anna K, Thongjuea, Supat, Bountra, Chas, Thakker, Rajesh V, Gorvin, Caroline M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345903/
https://www.ncbi.nlm.nih.gov/pubmed/34223822
http://dx.doi.org/10.1530/JME-21-0030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345903/
https://www.ncbi.nlm.nih.gov/pubmed/34223822
http://dx.doi.org/10.1530/JME-21-0030

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