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The bromodomain inhibitor JQ1+ reduces calcium-sensing receptor activity in pituitary cell lines
Corticotrophinomas represent 10% of all surgically removed pituitary adenomas, however, current treatment options are often not effective, and there is a need for improved pharmacological treatments. Recently, JQ1+, a bromodomain inhibitor that promotes gene transcription by binding acetylated histo...
Autores principales: | Lines, Kate E, Gluck, Anna K, Thongjuea, Supat, Bountra, Chas, Thakker, Rajesh V, Gorvin, Caroline M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345903/ https://www.ncbi.nlm.nih.gov/pubmed/34223822 http://dx.doi.org/10.1530/JME-21-0030 |
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