Role of Klotho in Hyperglycemia: Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration

Hyperglycemic conditions (HG), at early stages of diabetic nephropathy (DN), cause a decrease in podocyte numbers and an aberration of their function as key cells for glomerular plasma filtration. Klotho protein was shown to overcome some negative effects of hyperglycemia. Klotho is also a corecepto...

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Detalles Bibliográficos
Autores principales: Typiak, Marlena, Kulesza, Tomasz, Rachubik, Patrycja, Rogacka, Dorota, Audzeyenka, Irena, Angielski, Stefan, Saleem, Moin A., Piwkowska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345972/
https://www.ncbi.nlm.nih.gov/pubmed/34360633
http://dx.doi.org/10.3390/ijms22157867

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