Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease

Activation of the Ca(2+) activated Cl(−) channel TMEM16A is proposed as a treatment in inflammatory airway disease. It is assumed that activation of TMEM16A will induce electrolyte secretion, and thus reduce airway mucus plugging and improve mucociliary clearance. A benefit of activation of TMEM16A...

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Detalles Bibliográficos
Autores principales: Centeio, Raquel, Ousingsawat, Jiraporn, Cabrita, Inês, Schreiber, Rainer, Talbi, Khaoula, Benedetto, Roberta, Doušová, Tereza, Verbeken, Eric K., De Boeck, Kris, Cohen, Isaac, Kunzelmann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346050/
https://www.ncbi.nlm.nih.gov/pubmed/34360618
http://dx.doi.org/10.3390/ijms22157852

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