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Skin Mast Cell-Driven Ceramides Drive Early Apoptosis in Pre-Symptomatic Eczema in Mice

Atopic dermatitis (AD or eczema) is the most common chronic inflammatory skin disorder worldwide. Ceramides (Cer) maintain skin barrier functions, which are disrupted in lesional skin of AD patients. However, Cer status during the pre-lesional phase of AD is not well defined. Using a variation of hu...

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Detalles Bibliográficos
Autores principales: Robida, Piper A., Chumanevich, Alena P., Gandy, Alexa Orr, Fuseler, John W., Nagarkatti, Prakash, Nagarkatti, Mitzi, Oskeritzian, Carole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346072/
https://www.ncbi.nlm.nih.gov/pubmed/34360617
http://dx.doi.org/10.3390/ijms22157851