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Protective Effect of Memantine on Bergmann Glia and Purkinje Cells Morphology in Optogenetic Model of Neurodegeneration in Mice

Spinocerebellar ataxias are a family of fatal inherited diseases affecting the brain. Although specific mutated proteins are different, they may have a common pathogenetic mechanism, such as insufficient glutamate clearance. This function fails in reactive glia, leading to excitotoxicity and overact...

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Detalles Bibliográficos
Autores principales:	Shuvaev, Anton N., Belozor, Olga S., Mozhei, Oleg I., Khilazheva, Elena D., Shuvaev, Andrey N., Fritsler, Yana V., Kasparov, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346112/ https://www.ncbi.nlm.nih.gov/pubmed/34360588 http://dx.doi.org/10.3390/ijms22157822

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