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The Neurotrophin Receptor TrkC as a Novel Molecular Target of the Antineuroblastoma Action of Valproic Acid

Neurotrophins and their receptors are relevant factors in controlling neuroblastoma growth and progression. The histone deacetylase (HDAC) inhibitor valproic acid (VPA) has been shown to downregulate TrkB and upregulate the p75NTR/sortilin receptor complex. In the present study, we investigated the...

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Detalles Bibliográficos
Autores principales: Dedoni, Simona, Marras, Luisa, Olianas, Maria C., Ingianni, Angela, Onali, Pierluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346142/
https://www.ncbi.nlm.nih.gov/pubmed/34360553
http://dx.doi.org/10.3390/ijms22157790