TDP-43 and Inflammation: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

The abnormal mislocalisation and ubiquitinated protein aggregation of the TAR DNA binding protein 43 (TDP-43) within the cytoplasm of neurons and glia in the central nervous system (CNS) is a pathological hallmark of early-onset neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and fro...

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Detalles Bibliográficos
Autores principales: Bright, Fiona, Chan, Gabriella, van Hummel, Annika, Ittner, Lars M., Ke, Yazi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346169/
https://www.ncbi.nlm.nih.gov/pubmed/34360544
http://dx.doi.org/10.3390/ijms22157781

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