Rapid generation of maternal mutants via oocyte transgenic expression of CRISPR-Cas9 and sgRNAs in zebrafish

Maternal products are exclusive factors to drive oogenesis and early embryonic development. As disrupting maternal gene functions is either time-consuming or technically challenging, early developmental programs regulated by maternal factors remain mostly elusive. We provide a transgenic approach to...

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Detalles Bibliográficos
Autores principales: Zhang, Chong, Lu, Tong, Zhang, Yizhuang, Li, Jiaguang, Tarique, Imran, Wen, Fenfen, Chen, Aijun, Wang, Jiasheng, Zhang, Zhuoyu, Zhang, Yanjun, Shi, De-Li, Shao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346210/
https://www.ncbi.nlm.nih.gov/pubmed/34362733
http://dx.doi.org/10.1126/sciadv.abg4243

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