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Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation

Altered mitochondrial quality control and dynamics may contribute to neurodegenerative diseases, including Parkinson’s disease, but we understand little about these processes in neurons. We combined time-lapse microscopy and correlative light and electron microscopy to track individual mitochondria...

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Detalles Bibliográficos
Autores principales:	Li, Huihui, Doric, Zak, Berthet, Amandine, Jorgens, Danielle M., Nguyen, Mai K., Hsieh, Ivy, Margulis, Julia, Fang, Rebecca, Debnath, Jayanta, Sesaki, Hiromi, Finkbeiner, Steve, Huang, Eric, Nakamura, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346224/ https://www.ncbi.nlm.nih.gov/pubmed/34362731 http://dx.doi.org/10.1126/sciadv.abf6580

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