Metformin Alleviates Hepatic Steatosis and Insulin Resistance in a Mouse Model of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease by Promoting Transcription Factor EB-Dependent Autophagy

Nonalcoholic fatty liver disease (NAFLD) results from an abnormal accumulation of lipids within hepatocytes, and is commonly associated with obesity, insulin resistance, and hyperlipidemia. Metformin is commonly used to treat type 2 diabetes mellitus and, in recent years, it was found to play a pote...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Dan, Ma, Yicheng, Liu, Jianjun, Deng, Yi, Zhou, Bo, Wen, Yu, Li, Mingke, Wen, Daiyan, Ying, Yunyan, Luo, Sufeng, Shi, Chunjing, Pu, Guangyu, Miao, Yinglei, Zou, Chenggang, Chen, Yuanli, Ma, Lanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346235/
https://www.ncbi.nlm.nih.gov/pubmed/34366846
http://dx.doi.org/10.3389/fphar.2021.689111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346235/
https://www.ncbi.nlm.nih.gov/pubmed/34366846
http://dx.doi.org/10.3389/fphar.2021.689111

Ejemplares similares